Zhi-Ke He

Personal Informationㄩ

Professor of chemistry
Dept. of chemistry, Wuhan University
Wuhan, China,
Fax: +86-27-68754067
Experiencesㄩ B.S., 1987, Huazhong Normal University, Wuhan, China

Ph.D., 1995, Wuhan University, Wuhan, China
Humboldt research Fellowsㄛ1998 halle University; 2006 Bielefeld University; 2008 Dortmund UniversityㄛGermany
Postdoctoral Research Fellowㄛ2001-2003ㄛThe Hong Kong Polytechnic UniversityㄛHongkongㄛChina
Research Interestsㄩ His research interests focus on luminescent analysis. So far, he has published over 130 SCI papers. Moreover, Prof. He has been authorized 6 Patents.
Recent Foundation ( Partial )ㄩ 973 program, Microfluidic chip method and its application in infective diseaseㄛ2007CB714507
National Natural Science Foundation of China, Plant hormone detection and receptor identification based on Quantum dots, 90717111.
Selected Awardsㄩ 2009 The second prize of excellent teaching achievements of National higher education
2009 The first prize of excellent teaching achievements of Hubei province
2000 The second prize of natural science of Hubei province
Social Activitiesㄩ
Patentsㄩ (1). He Zhi-Ke, Chen Yan-Guo, Fluorescent sensor based on the conjugated polymer, Chinese National Invention Patent. CN 1004584117Cㄛissued Februaryㄛ2009.
(2) He Zhi-Ke, Liang Jian-GongㄛXie Hai-Yan, Pang Dai-Wen, Preparation of water-soluble nanoparticles, Chinese National Invention Patent. CN 1320974C, issued Juneㄛ2007
(3) He Zhi-Ke, Liang Jian-GongㄛPreparation of CdSe and its fluorescent solution, Chinese National Invention Patent. CN 1260771C, issued Juneㄛ2006
(4) Wong Kwok-Yin, Chi Chi-Ming, Lu Wei, He Zhi-Ke, Luminescent sensory material for organic-halogen compounds, and methods and apparatus utilization suchㄛAmerican patentㄛUS6,998,271, issued Februaryㄛ2006
Selected Publicationsㄩ 1ㄘLing-Zhi Liu, Xiao-Hu Dong, Wen-Long Lian, Xiao-Niu Peng, Zhi-Hong Liu, Zhi-Ke He, and Qu-Quan Wang, Homogeneous Competitive Hybridization Assay Based on Two-Photon Excitation Fluorescence Resonance Energy Transfer, Anal Chem, 2010, 82, 1381每1388e
2ㄘ Dan Zhao, Wing-Hong Chan, Zhi-Ke He and Ting QiuㄛQuantum Dot-Ruthenium Complex Dyads: Selective Recognition of Double-Strand DNA through Dual-color Fluorescence Detectionㄛ Anal. Chem.ㄛ2009, 81 (9), 3537-3543
3ㄘHai-Gang Li and Zhi-Ke HeㄛMagnetic bead-based DNA hybridization assay with chemiluminescence and chemiluminescent imaging detectionㄛAnalystㄛ2009ㄛ134ㄩ800-804
4ㄘShan Huang, Qi Xiao, Zhi-Ke He, Yi Liu, Philip Tinnefeld, Xiong Rui Su and Xiao Niu Peng, A high sensitive and specific QDs FRET bioprobe for Mnase, Chem Commun, 2008, 5990-5992
5ㄘDan Zhao, Juan Du, Yan-Guo Chen, Xing-Hu Ji, Zhi-Ke He, and Wing-Hong Chan, A Quencher-Tether-Ligand Probe and Its Application in Biosensor Based on Conjugated Polymer, Macromolecules, 2008ㄛ41ㄩ5373每5378
6ㄘ Ling-Zhi Liu, Geng-Hui Wei, Zhi-Hong Liu, Zhi-Ke He, Si Xiao, and Qu-Quan Wang, Homogeneous Immunoassay Based on Two-Photon Excitation Fluorescence Resonance Energy Transfer, Anal. Chem., 2008, 80(20), 7735-7741.
7ㄘLing-Zhi Liu, Geng-Hui Wei, Zhi-Hong Liu, Zhi-Ke He, Si Xiao, and Qu-Quan Wang, Two-Photon Excitation Fluorescence Resonance Energy Transfer with Small Organic Molecule as Energy Donor for BioassayㄛBioconjugate Chem. 2008, 19, 574每579
8ㄘ Ji-Jun Tang, Tao Yu, Lei Guo, Jian-Wei Xie, Ning-Sheng Shao, Zhi-Ke He, In vitro selection of DNA aptamer against abrin toxin and aptamer-based abrin direct detection, Biosensors and Bioelectronics,2007, 22 , 2456每2463
9ㄘ Jun-An Liu, Hai-Bing Li, Wei Wang, Hui-Bi Xu, Xiang-Liang Yang, Jian-Gong Liang, Zhi-Ke He, Use of Ester-Terminated Polyamidoamine Dendrimers for Stabilizing Quantum Dots in Aqueous Solutions, Small, 2006, 2( 8-9) , 999 每 1002
10ㄘ Juang-Hui Yu, Jian-Gong Liang, Zhi-Ke He and Meng-Xiang Sunㄛ Quantum Dot-Mediated Detection of 污-Aminobutyric Acid Binding Sites on the Surface of Living Pollen Protoplasts in TobaccoㄛChemistry & Biology, 2006, 13(7), 723-731

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